Combine the ground beef with the seasoning blend, worchestire sauce, eggs, breadcrumbs, and liquid smoke in a medium size mixing bowl. All the meatloaf mixture to sit at room temp for at least 30 minutes.
Preheat your air fryer on the hottest setting for 10 minutes. Make sure the basket or cooking surface is inside the air fryer. On the Ninja Foodi Pressure Cooker & Air Crisper, this is the broil (or grill) setting.
Mix the glaze ingredients in a small bowl and set aside
While the air fryer is preheating, compact your meatloaf mixture by throwing it back and forth between your hands for about 3 minutes. You want to compress the meat so your meatloaf holds together when slicing. Look for a smooth surface on the outside of your meatloaf and that is a good indicator that it is compacted enough.
Form your meatloaf. I like to make an oblong shape that is about 8" long and about 3-4" high. The shape you make will affect cooking time, so if you have a larger circumference, it will take longer to cook.
Place the meatloaf into the air fryer (no loaf pan needed) and select the air fry setting on 300°F/150°C and set the time for 50 minutes. Allow the meatloaf to air fry for 30 minutes without opening the air fryer, then take an internal temperature to determine how much longer it needs. In my test recipes, it has taken about 45 minutes. However, one time my meatloaf split in the middle and it only took 30 minutes.
About the time the internal temperature reaches 140℉/60℃ is the time you want to start applying the glaze. I like to apply a thin layer every 3-5 minutes until the meatloaf reaches an internal temperature of around 160-165℉/71-74℃ and then remove your meatloaf and let it rest for a full 10 minutes.
**If your meatloaf reaches a higher internal temperature (155-165℉/68-74℃) in the first 30 minutes, apply half of the glaze and increase the temperature to 400℉ and air fry for 2 minutes. Apply the remaining glaze and air fry another 2 minutes. Remove the meatloaf and let it rest a full 10 minutes.